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Journal of Tropical Pediatrics Advance Access published online on October 26, 2007
Journal of Tropical Pediatrics, doi:10.1093/tropej/fmm084
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© The Author [2007]. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oxfordjournals.org

Clinical, Laboratory and Radiological Parameters in Children with Dengue Fever and Predictive Factors for Dengue Shock Syndrome

Betty Chacko and Gayathri Subramanian

Sri Ramachandra Medical College and Research Institute, Porur, Chennai 600116, India

Correspondence: Dr Betty Chacko, Department of Paediatrics, Sri Ramachandra Medical College and Research Institute, Porur, Chennai 600116, India. E-mail: < bettychacko{at}hotmail.com> or < bettychacko{at}gmail.com>.


  Abstract

This article is a prospective study of the clinical, laboratory and radiological picture of children satisfying the case definition criteria of dengue by WHO admitted at Sri Ramachandra Medical College and Research Institute, a suburban tertiary referral centre, to determine the predictive factors for dengue shock syndrome (DSS). Data were analyzed by Chi-squared test and Student's t-test for significance after dividing the patients into two groups, those with and those without DSS for the same. Bleeding manifestations, presence of effusion on USG/X-ray, haematocrit >35%, WBC <4000/cumm, Na ≤130 meq/l, bicarbonate level of <18 mmol/l, deranged coagulation profile and serum glutamic pyruvic transaminase (SGPT) ≥40 IU were predictive of DSS.


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