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Journal of Tropical Pediatrics Advance Access published online on July 11, 2007
Journal of Tropical Pediatrics, doi:10.1093/tropej/fmm024
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© The Author [2007]. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oxfordjournals.org

Hemophagocytic Lymphohistiocytosis Associated with Visceral Leishmaniasis

Anil Tapisiz, Nursen Belet, Ergin Çiftçi, Erdal Ince and Ülker Dogru

Department of Paediatrics, Section of Infectious Diseases, Ankara University Medical School, Turkey

Correspondence: Anil Tapisiz, Turan Gunes Bulvari, Sedir Sitesi C2 Blok No:6, Or-an, 6450 Ankara, Turkey. Tel: +903124917707. E-mail < anlaktas{at}hotmail.com>.


  Abstract

Visceral leishmaniasis (VL), is a systemic disease caused by the dissemination of protozoan parasite Leishmania throughout the reticuloendothelial system. It may mimic or lead to several types of hematological disorders including hemophagocytosis. Infection associated hemophagocytic syndrome implicating Leishmania is very rare and often difficult to diagnose. Here, we describe a child with hemophagocytic lymphohistiocytosis (HLH) associated with VL.

Key Words: Leishmania • hemophagocytosis • children


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