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Journal of Tropical Pediatrics Advance Access published online on October 24, 2006
Journal of Tropical Pediatrics, doi:10.1093/tropej/fml040
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© The Author [2006]. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oxfordjournals.org

Original Papers

Fatal Encephalopathy and Renal Failure caused by Diethylene Glycol Poisoning

Pankaj Hari 1 *, Yogesh Jain 1, and Sushil Kumar Kabra 1

1 Department of Pediatrics, All India Institute of Medical Sciences, Ansari Nagar, New Delhi 110029, India

* To whom correspondence should be addressed.
Pankaj Hari, E-mail: pankajhari{at}hotmail.com


  Abstract

Diethylene glycol poisoning results in multiorgan dysfunction and requires a high index of suspicion for diagnosis. We report 11 patients of diethylene glycol poisoning, all of whom had renal failure and severe encephalopathy. The diagnosis was established by the presence of diethylene glycol in the paracetamol elixir consumed by these children; the amount of which ranged from 2.3 to 23% w/W. Consumption of large amount of toxin resulted in severe encephalopathy and high mortality in these children.


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