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Journal of Tropical Pediatrics Advance Access published online on May 31, 2005
Journal of Tropical Pediatrics, doi:10.1093/tropej/fmi034
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© The Author [2005]. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oupjournals.org

Original Papers

Progressive Multifocal Leukoencephalopathy (PML) Presenting as Intractable Dystonia in an HIV-Infected Child

Ira Shah 1* and Priya Chudgar 2

1 Department of Pediatric HIV, B. J. Wadia Hospital for Children, Mumbai, India
2 Department of Radiology, Nivaran CT Scan/MRI Centre, Mumbai, India

* To whom correspondence should be addressed.
Ira Shah, E-mail: irashah{at}pediatriconcall.com


  Abstract

Progressive multifocal leukoencephalopathy (PML) has been described in adult immunocompromised patients and has a progressive downhill course. Though dementia and motor disturbances have been described, intractable dystonia is a very unusual manifestation. In children, PML is very rare and often misdiagnosed as other central nervous system (CNS) encephalopathy. No definitive treatment is available.


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