Skip Navigation

Journal of Tropical Pediatrics 2002 48(6):335-339; doi:10.1093/tropej/48.6.335
© 2002 by Oxford University Press
This Article
Right arrow Full Text (PDF)
Right arrow E-letters: Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when E-letters are posted
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in ISI Web of Science
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrow Search for citing articles in:
ISI Web of Science (5)
Right arrowRequest Permissions
Google Scholar
Right arrow Articles by Cam, B. V.
Right arrow Articles by Heegaardd, E. D.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Cam, B. V.
Right arrow Articles by Heegaardd, E. D.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

Randomized Comparison of Oxygen Mask Treatment vs. Nasal Continuous Positive Airway Pressure in Dengue Shock Syndrome with Acute Respiratory Failure

B. V. Cam1, D. T. Tuan1, L. Fonsmark2, A. Poulsen3, N. M. Tien1, H. M. Tuan1 and E. D. Heegaardd4

1 Department of Intensive Care, Pediatric Hospital No. 1, Ho Chi Minh City, Vietnam 2 Department of Infectious Diseases, University State Hospital, Copenhagen Denmark 3 Department of Pediatrics, University State Hospital, Copenhagen Denmark 4 Department of Clinical Microbiology, University State Hospital, Copenhagen Denmark

Dengue hemorrhagic fever (DHF) is caused by dengue virus. Patients with DHF grade 3–4, termed Dengue Shock Syndrome (DSS), may develop acute respiratory failure after initial fluid resuscitation. Previously, these patients were treated with oxygen on a nasal cannula, or if necessary with tracheal intubation and mechanical ventilation. In the present prospective randomized study, we compared the effectiveness of oxygen treatment administered by a face mask vs. nasal continuous positive airway pressure (NCPAP). Morbidity, mortality, and supportive treatment was evaluated. Thirty-seven patients with DSS complicated by respiratory failure were enrolled. On admission and after 30 min of treatment, clinical and paraclinical data were obtained. Chest X-ray revealed pleural effusion in 92 per cent and showed interstitial oedema in 33 per cent. After 30 min of treatment the respiratory rate decreased significantly in the NCPAP group (p < 0.05), while SaO2 and PaO2 increased in both groups (p < 0.01). However, subsequently a significant difference of unresponsiveness to treatment between the oxygen mask group and the NCPAP group (13/19 vs. 4/18, p < 0.01) was noted. Complications of NCPAP or oxygen mask treatment were not documented. We conclude that NCPAP is useful in improving the management of acute respiratory failure in children with DHF/DSS in dengue-endemic areas.


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?


This article has been cited by other articles:


Home page
 Am J Trop Med HygHome page
N. T. HUNG, N. T. LAN, H.-Y. LEI, Y.-S. LIN, L. B. LIEN, K.-J. HUANG, C.-F. LIN, D. Q. HA, V. T. Q. HUONG, L. T. MY, et al.
VOLUME REPLACEMENT IN INFANTS WITH DENGUE HEMORRHAGIC FEVER/DENGUE SHOCK SYNDROME
Am J Trop Med Hyg, April 1, 2006; 74(4): 684 - 691.
[Abstract] [Full Text] [PDF]


Disclaimer:
Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.