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Journal of Tropical Pediatrics 2000 46(3):172-175; doi:10.1093/tropej/46.3.172
© 2000 by Oxford University Press
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Brief report. Predictors of failure of nasal continuous positive airway pressure in treatment of preterm infants with respiratory distress syndrome

NY BooA,Z, AL ZuraidahB, NL LimB and MA ZulfiqarC

A Department of Paediatrics, Faculty of Medicine, C Department of Radiology, University Kebangsaan Malaysia, Jalan Tenteram, 56000 Cheras, Kuala Lumpur, Malaysia B Department of Paediatrics, Institute of Paediatrics, Kuala Lumpur Hospital, Kuala Lumpur, Malaysia Z Corresponding author E-mail: nyboo@hukln.ukm.my

A case-control study was carried out on 97 consecutive preterm (<37 weeks) infants to determine predictors associated with failure of nasal continuous positive airway pressure (CPAP) in the treatment of respiratory distress syndrome (RDS). Logistic regression analysis showed that only three risk factors were significantly associated with failed CPAP. These were: moderate or severe RDS (odds ratio: 5.9; 95 per cent confidence interval (CI): 2.2-16.0); septicemia during CPAP therapy (OR: 8.8; 95 per cent: CI 1.5-50.7); and pneumothorax during CPAP therapy (odds ratio: 6.9; 95 per cent: CI 1.1-41.7).


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This article has been cited by other articles:


Home page
 Arch. Dis. Child. Fetal Neonatal Ed.Home page
C Booth, M H Premkumar, A Yannoulis, M Thomson, M Harrison, and A D Edwards
Sustainable use of continuous positive airway pressure in extremely preterm infants during the first week after delivery
Arch. Dis. Child. Fetal Neonatal Ed., November 1, 2006; 91(6): F398 - F402.
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