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Journal of Tropical Pediatrics 1999 45(2):106-107; doi:10.1093/tropej/45.2.106
© 1999 by Oxford University Press
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Case report. Imerslund-Gräsbeck syndrome in an African patient

DK StonesA1 and M FerreiraA2

Departments of A1 Paediatrics and Child Health and A2 Haematology, University of Free State, Bloemfontein, 9301, South Africa

Imerslund-Gräsbeck syndrome (IGS) is a rare cause of megaloblastic anaemia in young children. We wish to report the first case, described from Africa. The diagnosis of IGS was made on the findings of a low vitamin B12 level, mild proteinuria, and a vitamin B12 absorption test unaffected by the intrinsic factor. The patient responded well to treatment with intramuscular vitamin B12.


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