© 1995 by Oxford University Press
research-article |
Pattern of Hepatitis A and Hepatitis B Virus Markers in Cases of Acute Sporadic Hepatitis and in Healthy School Children from North West India
*Sections of Clinical Gastroenterology (Pediatric Gastroenterology and Gastroemerology-II) PGIMER Chandigarh 160012, India
**virology, Superspeciality of Gastroenterology PGIMER, Chandigarh 160012, India
***Enzymology, Superspeciality of Gastroenterology PGIMER, Chandigarh 160012, India
Dr B. R. Thapa, Division of Pediatric Gastroenterology, Postgraduate Institute of Medical Education & Research, Chandigarh 160012, India.
The pattern of viral markers in acute sporadic hepatitis in 329 children and those in 334 healthy school children from North West India were studied. Hepatitis A was found to be the commonest infection in sporadic cases (78 per cent). Of these, 86 per cent were under 10 years and 50 per cent less than S years of age. Hepatitis B was positive in 8 per cent, non-A non-B in 13 per cent, A as well as B in 1 per cent, and none had Delta vims infection. Viral markers in healthy school children showed anti-HAV IgG positivity in 96 and 85 per cent in those belonging to low and high socio-economic groups, respectively, indicating past infection. HBsAg was positive in 1 per cent of cases. Viral hepatitis is an important public health problem in children and warrants active immunization.