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Journal of Tropical Pediatrics 1995 41(4):230-233; doi:10.1093/tropej/41.4.230
© 1995 by Oxford University Press
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Serum Vitamin A (Retinol) Concentrations and Association with Respiratory Disease in Premature Infants

A. Coutsoudis, M. Adhikari and H. M. Coovadia

Department of Paediatrics and Child Health, University of Natal South Africa

Correspondence: Anna Coutsoudis, Department of Paediatrics and Child Health, PO Box 17039, Congella 4013, South Africa.

Vitamin A has been shown to be important in immunity and in differentiation of epithelial tissues. Serum concentrations of vitamin A (retinol) were measured at birth, in 54 preterm and 24 full term infants. Vitamin A concentrations were significantly lower in the preterm compared to the full term infants (9.81±0.58 µg/dl v. 15.58±1.00 µg/dl, P = 0.0001). Serum retinol and birth weight were positively correlated (r = 0.39, P = 0.0004); however, there was no correlation between maternal and infant vitamin A concentrations. The initially reduced vitamin A levels in the preterm infants were not associated with respiratory distress syndrome or pneumonia.


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