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Journal of Tropical Pediatrics 1989 35(1):24-26; doi:10.1093/tropej/35.1.24
© 1989 by Oxford University Press
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Enuresis in Sickle Cell Disease. I. Prevalence Studies

Olu Akinyanju, MD, FRCP*,, Olatoye Agbato, BSc, MBBS, FMCPaed. (Nig)**, A. Oluwole Ogunmekan, MD, FRCPE** and Joseph U. Okoye, MBBS

*Department of Medicine of the College of Medicine of the University of Lagos and the Lagos University Teaching Hospital Lagos, Nigeria
**Department of Paediatrics, of the College of Medicine of the University of Lagos and the Lagos University Teaching Hospital Lagos, Nigeria

Olu Akinyanju, MD, Haematology Unit, Department of Medicine, College of Medicine, PMB 12003, Lagos, Nigeria.

The prevalence of enuresis was determined by parental interview in Nigerian children with sickle cell anaemia and in age-matched controls without sickle haemoglobinopathy. There were a total of 209 subjects with sickle cell anaemia (SCA) in steady state and 200 controls of both sexes aged from 2 to 20 years. The prevalence of enuresis was 41.6 per cent in those with SCA and 18.5 per cent in the controls. In subjects who were 4 years or more the prevalences were 36.8 and 21 per cent, respectively. These differences were highly significant (P<0.001).

There was a significant preponderance of males among enuretic control subjects (2.6 to 1) who were aged 4 years or more (P<0.05) which was not apparent in the sickle cell subjects at any age or in the controls below the age of 4 years.


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