© 1980 by Oxford University Press
research-article |
Tuberculous Meningitis and BCG Vaccination in Burmese Children
Children's Hospital Rangoon, Burma
One hundred and fifty consecutive cases of tuberculous meningitis admitted to Children's Hospital in Rangoon were analysed and the presenting symptoms, linical manifestations, investigative findings and the factors influencing the outcome are presented.At the time of discharge, 61 children (40.7 %) had no motor neurological deficit, 59 (39.3 %) were left with motor neurological deficit and 30 (20%) died. The children were not followed up long enough to estimate their mental state. The factors which increase mortality and sequelae rates were young age, change in level of consciousness on admission, motor paralyses or neurological deficit on admission, high cerebro-spinal fluid protein level of more than 300 mg/100 ml and associated miliary tuberculosis. 39 children had received BCG vaccinations in their newborn period and the possible causes for ineffective protection against tuberculous meningitis in Burma are discussed.