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Journal of Tropical Pediatrics Advance Access published online on October 20, 2009
Journal of Tropical Pediatrics, doi:10.1093/tropej/fmp092
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© The Author [2009]. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oxfordjournals.org

Brief Report

A Pilot Study of Comparison of BCPAP vs. VCPAP in Preterm Infants with Early Onset Respiratory Distress

Amit Tagarea, Sandeep Kadama, Umesh Vaidyaa, Anand Pandita and Sanjay Patoleb,c

aDivision of Neonatology, Department of Pediatrics, KEM Hospital, Rasta Peth, Pune 411011, India
bDepartment of Neonatal Pediatrics, King Edward Memorial Hospital for Women, Perth,Western Australia
cUniversity of Western Australia, Perth,Western Australia

Correspondence: Sandeep Kadam, Division of Neonatology, Department of Pediatrics, KEM Hospital, Rasta Peth, Pune 411011, India. E-mail: <drsandeepkadam{at}yahoo.com>.


  Abstract

Background: Bubble continuous positive airway pressure (BCPAP) is a low-cost nasal CPAP delivery system with potential benefits for developing nations. The objective of the study was to compare the efficacy and safety of BCPAP with ventilator CPAP (VCPAP) in preterm neonates with moderate respiratory distress.

Methods: In a pilot randomized controlled trial, 30 preterm neonates (gestation <37 weeks) with Silverman–Anderson score between 5 to 7 and oxygen requirement >30% within first 6 h of life were randomly allocated to BCPAP or VCPAP after informed parental consent. Proportion of neonates with success or failure, while using the allocated mode of CPAP delivery (primary outcome) was compared.

Results: The success rate was comparable [VCPAP: 80% (12/15) vs. BCPAP: 87% (13/15)] between the two groups. Dislodgement was commonest problem with equal frequency [10/15, (67%)] in each group.

Conclusion: BCPAP appears to be a promising method of CPAP delivery in preterm neonates with moderate respiratory distress.


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