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Journal of Tropical Pediatrics Advance Access published online on April 28, 2009
Journal of Tropical Pediatrics, doi:10.1093/tropej/fmp026
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© The Author [2009]. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oxfordjournals.org

Human Bocavirus in Very Young Infants Hospitalized with Acute Respiratory Infection in Northeast Brazil

Edna Lucia Souzaa, João Gabriel Ramosb, José Luiz Proença-Módenac, Andréa Dinizb, Gerson Carvalhob, Isolina Ciuffod, César A. Araújo-Netoe, Sandra Cristina Andradeb, Leda Solano Souzaf, Eurico Arrudac and Luciana Silvaa

aDepartment of Pediatrics of School Medicine, Federal University of Bahia, Brazil, bSchool Medicine, Federal University of Bahia, Brazil, cSchool of Medicine of Ribeirão Preto, University of São Paulo, Brazil, dCentral Laboratory of Public Health, Salvador, Brazil and eDepartment of Image Diagnosis of School Medicine, Federal University of Bahia, Brazil, fSchool Medicine of Faculty of Technology and Sciences, Salvador, Brazil

Correspondence: Edna Lucia Souza. E-mail <ednalu{at}ufba.br>.

Abstract


  Abstract

A cross-sectional study was carried out over a period of 12 months to investigate the occurrence of human bocavirus (HBoV) infection in infants hospitalized for respiratory infections in a teaching hospital in Salvador, Brazil, and to describe the clinical manifestations of this infection. Nasopharyngeal aspirates were collected from the children and immunofluorescence and polymerase chain reaction were performed to investigate the presence of respiratory viruses. HBoV was detected in 4 out of 66 patients. Two of the HBoV-positive infants were co-infected with other viruses. The principal clinical findings in HBoV-positive children were: nasal obstruction, catarrh, cough, fever and dyspnea. This study revealed HBoV infection in children aged <2 months, suggesting that the infection may occur at a very early age.


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