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Journal of Tropical Pediatrics Advance Access published online on March 17, 2009
Journal of Tropical Pediatrics, doi:10.1093/tropej/fmp019
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© The Author [2009]. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oxfordjournals.org

Brief Report

A Study of Profile of Ventilator-associated Pneumonia in Children in Punjab

Harsh Sharmaa, Daljit Singhb, Puneet Poonib and Urmil Mohanc

aDepartment of Pediatrics, Indira Gandhi Memorial Hospital, Male, Maldives
bDepartment of Pediatrics, Dayanand Medical College and Hospital, Ludhiana, Punjab, India
cDepartment of Microbiology, Dayanand Medical College and Hospital, Ludhiana, Punjab, India

Correspondence: Harsh Sharma, 492, Guru Gobind Singh Avenue, Jalandhar City, Punjab, India. Tel: 098728-78171; Fax: 0164-2742901. E-mail: <dr_harsh75{at}yahoo.co.in>.


  Abstract

Objectives: To determine incidence, related factors, outcome, bacterial organisms and their sensitivity patterns with regard to ventilator-associated pneumonia (VAP) in children.

Setting: Level III PICU of a tertiary care center.

Design: Prospective cohort study.

Methods: Children in the age group of 1 month to 15 years, admitted to the pediatric intensive care unit requiring ventilatory support (V.I.P.BIRD infant-Pediatric ventilator) for at least 48 h. Clinical criteria used to define VAPs were the same as used by and Elward et al. and Salata et al.

Results: Forty patients met the inclusion criteria and 8 (20%) had VAP. The risk factor significantly related with development of VAP was the use of H2 blockers (Ranitidine) for >2 days. All other related factors were not significantly related to occurrence of VAP.

Conclusion: Use of H2 blockers (Ranitidne) is associated with higher incidence of VAP in children.

Key Words: ventilator-associated Pneumonia • pediatric intensive care unit • children


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