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Journal of Tropical Pediatrics Advance Access published online on March 15, 2008
Journal of Tropical Pediatrics, doi:10.1093/tropej/fmn021
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© The Author [2008]. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oxfordjournals.org

Epidemiology of Rotavirus Infection in North-western Nigeria

M. Aminua, A. A. Ahmada, J. U. Umohb, J. Dewarc, M. D. Esonac and A. D. Steelec

aFaculty of Science, Department of Microbiology, Ahmadu Bello University, Zaria, Nigeria
bFaculty of Veterinary Medicine, Department of Public Health and Preventive Medicine, Ahmadu Bello University, Zaria, Nigeria
cMRC/MEDUNSA Diarhoeal Pathogens Research Unit, University of Limpopo, Medunsa Campus, Pretoria, South Africa

Correspondence: Dr M. Aminu, Department of Microbiology, Faculty of Science, Ahmadu Bello University, Zaria, Nigeria. E-mail < maryamaminu{at}yahoo.com>.


  Abstract

Rotaviruses (RV) are associated with ~33 000 deaths in children <5 years of age annually in Nigeria. However, limited data exit on RV infection in north-western Nigeria. During July 2002 to July 2004, 1063 (869 diarrhoeic and 194 control) stool samples were collected from children <5 years of age presenting with diarrhoea in north-western Nigeria. The stools were analysed for RV antigen and further characterized by antigenic and genomic methods. RV was detected in 18% of children with diarrhoea and 7.2% of the age-matched case controls. The highest RV burden was detected in children <6-months-old. Long electropherotypes and VP6 subgroup I + II specificity predominated.


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