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Journal of Tropical Pediatrics Advance Access originally published online on May 31, 2005
Journal of Tropical Pediatrics 2005 51(6):380-382; doi:10.1093/tropej/fmi034
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© The Author [2005]. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oxfordjournals.org

Case Report

Progressive Multifocal Leukoencephalopathy (PML) Presenting as Intractable Dystonia in an HIV-Infected Child

Ira Shaha and Priya Chudgarb

a Department of Pediatric HIV, B. J. Wadia Hospital for Children, Mumbai, India b Department of Radiology, Nivaran CT Scan/MRI Centre, Mumbai, India

Correspondence: Dr Ira Shah, MD, DNB, FCPS, DCH, 240 D. Walkeshwar Road, Malabar Hill, Mumbai 400006, India. E-mail <irashah{at}pediatriconcall.com>.

Progressive multifocal leukoencephalopathy (PML) has been described in adult immunocompromised patients and has a progressive downhill course. Though dementia and motor disturbances have been described, intractable dystonia is a very unusual manifestation. In children, PML is very rare and often misdiagnosed as other central nervous system (CNS) encephalopathy. No definitive treatment is available.


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