Skip Navigation

Journal of Tropical Pediatrics 2004 50(4):234-238; doi:10.1093/tropej/50.4.234
© 2004 by Oxford University Press
This Article
Right arrow Full Text (PDF)
Right arrow E-letters: Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when E-letters are posted
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in ISI Web of Science
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrow Search for citing articles in:
ISI Web of Science (16)
Right arrowRequest Permissions
Google Scholar
Right arrow Articles by Erdeve, O.
Right arrow Articles by Dallar, Y.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Erdeve, O.
Right arrow Articles by Dallar, Y.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

Brief Reports

The Probiotic Effect of Saccharomyces boulardii in a Pediatric Age Group

Omer ErdeveA1,, Ulku TirasA1 and Yildiz DallarA1

A1 Ankara Education and Research Hospital, Ankara, Turkey

The aim of this study was to determine the efficacy of S. boulardii in diarrhea associated with commonly used antibiotics such as sulbactam-ampicillin (SAM) and azithromycin (AZT). Four hundred and sixtysix patients were assigned to four different groups as follows: group 1: 117 patients receiving SAM alone; group 2: 117 patients receiving SAM and S. boulardii; group 3: 105 patients receiving AZT alone; group 4: 127 patients receiving AZT and S. boulardii. Antibiotic-associated diarrhea was seen in 42 of the 222 patients (18.9 per cent) receiving an antibiotic without the probiotic, and in 14 of the 244 patients (5.7 per cent) who received both the probiotic and the antibiotic (p < 0.05). In the group receiving SAM where S. boulardii use was found to be significant, the use of S. boulardii decreased the diarrhea rate from 32.3 to 11.4 per cent in the 1–5 years age group (p < 0.05). This is a pioneering study investigating combined antibiotic and probiotic use in pediatric diarrhea patients.

* Correspondence: Dr Omer Erdeve, S.B. Ankara Egitim ve Arastirma Hastanesi, Pediatri Klinigi 06320, Ulucanlar, Ankara, Turkey. E-mail <omererdeve{at}yahoo.com>


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?




Disclaimer:
Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.