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Journal of Tropical Pediatrics 2004 50(3):185-186; doi:10.1093/tropej/50.3.185
© 2004 by Oxford University Press
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Case Reports

Osteopetrorickets

Chellam KirubakaranA1,, Kala Ranjini R.A1, Julius X. ScottA1, Mona BaskerA1 and Gibikote SridharA2

A1 Department of Child Health Unit II, Christian Medical College, Vellore, India A2 Department of Radiology, Christian Medical College, Vellore, India

Rickets is a paradoxical complication of osteopetrosis resulting from the inability of the osteoclasts to maintain a normal calcium–phosphorus balance in the extracellular fluid. Detection of rickets in a child with osteopetrosis is necessary, because treatment of the rickets with vitamin D leads to improvement in activity, decrease in irritability, improvement of appetite, and protects against recurrent respiratory tract infections. If bone marrow transplantation is feasible, then for better results, rickets should be completely treated prior to the transplantation.

* Correspondence: Dr Chellam Kirubakaran, Professor and Head of Department of Child Health Unit II and Pediatric Hemato-Oncology, Christian Medical College, Vellore 632004, India. E-mail <child2{at}cmcvellore.ac.in>.


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