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Journal of Tropical Pediatrics 2001 47(3):132-135; doi:10.1093/tropej/47.3.132
© 2001 by Oxford University Press
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The Effect of Iron Supplementation on Visual-evoked Potentials in Infants with Iron-deficiency Anemia

S. Ümit Sarici1, Vedat Okutan1, M. Rusen Dündaröz1, A. Muhittin Serdar2, Ridvan Akin1, Gülhis Deda3 and Erdal Gökçay1

1 Department of Pediatrics, Gülhane Military Medical Academy, Ankara, Turkey 2 Department of Biochemistry, Gülhane Military Medical Academy, Ankara, Turkey 3 Department of Pediatrics, Ankara University School of Medicine, Ankara, Turkey

Flash visual-evoked potentials were studied in 20 infants with iron-deficiency anemia to determine the effect of iron deficiency on visual function by using visual-evoked potentials in this type of anemia. After iron therapy for 12 weeks, visual-evoked potentials were retested in these otherwise healthy infants. All infants showed an excellent hematological response to iron therapy. Post-treatment visual-evoked potential N2 latencies (negative deflections) decreased significantly compared to the pre-treatment values (p < 0.05). These results suggest that iron-deficiency anemia causes subclinical visual impairment, and visual-evoked potentials may be a useful non-invasive means of detecting subtle effects of nutritional deficiencies and monitoring the nutritional status of infants.


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