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Journal of Tropical Pediatrics 2000 46(4):246-248; doi:10.1093/tropej/46.4.246
© 2000 by Oxford University Press
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Case report. Adenotonsillar hypertrophy: a precipitating factor of cerebrovascular accident in a child with sickle cell anaemia

YA WaliA,Z, Z Al-LamkiA, H SolimanA and H Al-OkbiB

A Department of Child Health, Hematology/Oncology Unit, Sultan Qaboos University, Sultanate of Oman B Department of Surgery, College of Medicine, Sultan Qaboos University, Sultanate of Oman Z Corresponding author address: Child Health Department, College of Medicine, SQU, PO Box 35, Al-Khod 123, Sultanate of Oman Tel: 00968 515137 Fax: 00968 515136 E-mail: yawali@squ.edu.om

Cerebrovascular accident is one of the most serious complications of sickle cell anaemia. The specific factors that predispose patients with sickle cell anaemia to stroke are increased disease severity, higher baseline white blood cell count and lower baseline hematocrits. Likewise the presence of a co-existent alpha thalassemia trait and/or high fetal hemoglobin (HbF%) may reduce the risk. We report a child with sickle cell anaemia and marked adenotonsillar hypertrophy resulting in obstructive sleep apnea syndrome. There was no other known risk factor for developing cerebrovascular accident in this child during her hospitalization for adenotonsillectomy.


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