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Journal of Tropical Pediatrics 2000 46(1):21-24; doi:10.1093/tropej/46.1.21
© 2000 by Oxford University Press
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Viral isolates during febrile neutropaenia in children with cancer

R YusA, MF CottonA,Z, G WesselsA, PB HesselingA, R BesterB and EJ van RensburgB

A Department of Paediatrics and Child Health, Faculty of Medicine, University of Stellenbosch and Tygerberg Hospital, PO Box 19063, Tygerberg, 7505, South Africa B Department of Medical Virology, University of Stellenbosch and Tygerberg Hospital, Tygerberg, South Africa Z Corresponding author Fax: 27 21 938 9138 E-mail: mcot@maties.sun.ac.za

We prospectively studied South African children with cancer for viral isolates during episodes of febrile neutropaenia. Viruses were found in seven (31.8 per cent) and bacteria in five (22.7 per cent) of 22 episodes. The most common isolate was the herpes simplex virus and the most common source was from nasopharyngeal aspirates. There was no dual detection of viral and bacterial isolates. This study emphasizes the important contribution of viruses to febrile neutropaenia.


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