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Journal of Tropical Pediatrics 1999 45(3):168-169; doi:10.1093/tropej/45.3.168
© 1999 by Oxford University Press
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Brief report. Serum-free carnitine levels in children with heart failure

AT ErgürZ, F TanzerZ and Ö ÇetinkayaZZ

Departments of Z Pediatrics and ZZ Biochemistry, Faculty of Medicine, Cumhuriyet University, Siva, Turkey Corresponding author at: Örtülüpinar mah., Orhan Kurt Sitesi, Yakin Apt No 6, Daire 2, 58030 Sivas, Turkey

The serum-free carnitine (SFC) levels of 91 children with heart failure (HF) and of a control group consisting of 30 healthy children were measured. Twenty-four of 91 children with HF were administered oral L-carnitine. The mean SFC level of children with HF (20.16±0.30 nmol/l) was significantly lower than that of the control group (38.98±0.79 nmol/ml) (<0.01). Mean SFC levels of 24 patients, after L-carnitine administration, increased significantly (p <0.01). Patients administered L-carnitine displayed a marked difference in time taken for clinical improvement compared with those not given oral L-carnitine.


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