Skip Navigation

Journal of Tropical Pediatrics 1999 45(3):139-142; doi:10.1093/tropej/45.3.139
© 1999 by Oxford University Press
This Article
Right arrow Full Text (PDF)
Right arrow E-letters: Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when E-letters are posted
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in ISI Web of Science
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrow Search for citing articles in:
ISI Web of Science (2)
Right arrowRequest Permissions
Google Scholar
Right arrow Articles by Cliff, J
Right arrow Articles by Gani, A
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Cliff, J
Right arrow Articles by Gani, A
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

Ankle clonus and thiocyanate, linamarin, and inorganic sulphate excretion in school children in communities with konzo, Mozambique

J CliffZ, D NicalaZZ, F SauteZ, R GivragyZ, G AzambujaZ, A TaelaZ, L ChavaneZ and A GaniZZZ

Z Faculdade de Medicina, Universidade Eduardo Mondlane, Maputo, Mozambique ZZ Direcção Provincial de Saúde, Nampula, Mozambique ZZZ Repartição de Nutrição, Ministério de Saúde, Maputo, Mozambique

We examined 397 school children for ankle clonus in five communities in three district affected by konzo, spastic paraparesis associated with cassava consumption. From a subsample of 131 children, we analysed urine specimens for urinary thiocyanate, linamarin, and inorganic sulphate. The proportion of children with clonus varied between sites, ranging from 4 to 22 per cent. Geometric mean thiocyanate, linamarin, and inorganic sulphate concentrations were 163 and 60 µmol/l and 4.4 mmol/l, respectively. Children with ankle clonus had higher urinary thiocyanate concentrations. We recommend prevention to reduce cyanide exposure and further monitoring of cyanide exposure and neurological damage in these communities.


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?




Disclaimer:
Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.