Skip Navigation

Journal of Tropical Pediatrics 1998 44(2):70-72; doi:10.1093/tropej/44.2.70
© 1998 by Oxford University Press
This Article
Right arrow Full Text (PDF)
Right arrow E-letters: Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when E-letters are posted
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrow Search for citing articles in:
ISI Web of Science (3)
Right arrowRequest Permissions
Google Scholar
Right arrow Articles by Mohammad, A. M.
Right arrow Articles by Bajakian, K. M.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Mohammad, A. M.
Right arrow Articles by Bajakian, K. M.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

research-article

Sickle Cell Disease in Bahrain: Coexistence and Interaction with Glucose-6-phosphate Dehydrogenase (G6PD) Deficiency

Akbar M. Mohammad, MD, FAAP, Kasim O. Ardatl, MD, FAAP and Koharik M. Bajakian

Department of Pediatrics, College of Medicine and Medical Sciences, Arabian Gulf University Bahrain

The object was to determine the frequency of glucose-6-phosphate dehydrogenase in Bahraini individuals with HbS as compared to those without HbS. Haemolysates of erythrocytes from 310 Bahraini individuals attending Health Centres were obtained, electrophoresed on cellulose acetate at PH 8.2–8.6, and stained for G6PD. HbS was present in 125 Individuals (study group) and in 185 only HbA was present (control group). G6PD deficiency (very low to undetectable) was identified in 59 samples (47 per cent) of the study group and 35 (19 per cent) of the control group. A positive correlation between G6PD deficiency and HbS is present in Bahraini individuals tested. This is similar to the situation in the Eastern Province of Saudi Arabia. We speculate that the observation could be explained on the basis of historic endemicity of Falciparum malaria in both regions on the East coast of the Saudi Peninsula.


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?


This article has been cited by other articles:


Home page
 CVIHome page
N. Mahdi, K. Al-Ola, A. M. Al-Subaie, M. E. Ali, Z. Al-Irhayim, A. Q. Al-Irhayim, and W. Y. Almawi
HLA Class II Haplotypes Distinctly Associated with Vaso-Occlusion in Children with Sickle Cell Disease
Clin. Vaccine Immunol., April 1, 2008; 15(4): 729 - 731.
[Abstract] [Full Text] [PDF]


Disclaimer: Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.