Skip Navigation

Journal of Tropical Pediatrics 1997 43(3):178-181; doi:10.1093/tropej/43.3.178
© 1997 by Oxford University Press
This Article
Right arrow Full Text (PDF)
Right arrow E-letters: Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when E-letters are posted
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrow Search for citing articles in:
ISI Web of Science (7)
Right arrowRequest Permissions
Google Scholar
Right arrow Articles by Chattopadhya, D.
Right arrow Articles by Kumari, S.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Chattopadhya, D.
Right arrow Articles by Kumari, S.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

brief-report

Sexually-transmitted Disease (STD) Markers in Multitransfused Children in Relation to Human Immunodeficiency Virus Type-1 (HIV-1) Infection: Impact of STD Markers in Blood Donors

D. Chattopadhya, MD*,, R. Aggarwal, MSc, MPhil*, C. Prakash, MD, DNB**, S. Sen, MD*** and S. Kumari, MD {dagger}{dagger}

*AIDS Reference Laboratory, National Institute of Communicable Diseases Delhi - 110 054, India
**Hepatitis Laboratory, National Institute of Communicable Diseases Delhi - 110 054, India
***Department of Pediatrics, Charak Palika Hospital, Moti Bagh New Delhi - 110 021, India

{dagger}Dr D. Chattopadhya, AIDS Reference Laboratory, National Institute of Communicable Diseases, 22 Sham Nath Marg. Delhi - 110 054, India

Association of serological markers for various sexually transmitted diseases (STDs) with Human Immunodeficiency Virus type 1 (HIV-1) infection among heterosexually promiscuous blood donors is well recognized. However, possibility of similar association among children receiving transfusion from these donors has not been adequately explored. Study on the association of some STD markers with HIV-1 infection in multitransfused (MT) children showed that both HIV-1 positive and HIV-1 negative groups of children had significantly higher prevalence of hepatitis B virus (HBV) markers, i.e. HBsAg (23 and 30 per cent), anti-HBs (46 and 57 per cent), anti-HBc (18 and 23 per cent), antibodies to cytomegalovirus of IgM class (36 and 37 per cent) and IgG class (72.7 and 70 per cent), IgG antibodies to Herpes Simplex Virus type-2 (23 and 23 per cent) compared to control group. However, seropositivity for HIV-1 infection could not be attributed as a risk factor for any of these markers in the group of MT children. On the contrary, significant association of and HBc, anti HCV, CMV IgG and antitreponemal antibody with HIV-1 infection could be recorded in the group of blood donors. It appeared that due to low prevalence of HIV-1 infection among blood donors in India, both HIV-1 positive and HIV-1 negative groups of MT children received transfusion from HIV negative donors predominantly resulting in a comparable prevalence of STD markers in both the groups of MT children due to cumulative effect of transfusion from HIV-1 negative donors.


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?


This article has been cited by other articles:


Home page
 J Trop PediatrHome page
S. Onkar Shivraj, D. Chattopadhya, G. Grover, A. Kumar, and U. K. Baveja
Role of HCV Coinfection Towards Disease Progression and Survival in HIV-1 Infected Children: A Follow-Up Study of 10 Years
J Trop Pediatr, June 1, 2006; 52(3): 206 - 211.
[Abstract] [Full Text] [PDF]


Disclaimer:
Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.