Skip Navigation

Journal of Tropical Pediatrics 1997 43(3):143-148; doi:10.1093/tropej/43.3.143
© 1997 by Oxford University Press
This Article
Right arrow Full Text (PDF)
Right arrow E-letters: Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when E-letters are posted
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrowRequest Permissions
Google Scholar
Right arrow Articles by Bhutta, Z. A.
Right arrow Articles by Yusuf, K.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Bhutta, Z. A.
Right arrow Articles by Yusuf, K.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

research-article

Profile and Outcome of the Respiratory Distress Syndrome Among Newborns in Karachi: Risk Factors for Mortality

Zulfiqar Ahmed Bhutta and Kamran Yusuf

Department of Paediatrics, The Aga Khan University Hospital P. O. Box 3500, Stadium Road, Karachi, Pakistan

Although survival data on very low birth weight (VLBW) infants from developing countries indicates that mortality rates are high, there is considerable disagreement on the relative contribution of respiratory distress syndrome to neonatal morbidity and mortality. With improving facilities for newborn care, it is now possible to provide basic respiratory support to some babies with RDS in selected centres. We prospectively evaluated the profile and outcome of newborn infants with respiratory distress admitted to the newborn services at Aga Khan University Hospital in Karachi. The overall mortality for newborns with documented RDS was 81/200 (41 per cent), and was highest (70 per cent) for babies weighing <1000g at birth. Unlvariate and logistic regression analysis of factors significantly associated with high risk of dying despite respiratory support, included low apgar score at one minute (P = 0.003), admission AaDO2 value >400 (P = 0.001), development of acute renal failure (Relative risk 6.2, 95 per cent confidence interval 1.0–40.0), intraventricular haemorrhage (RR 2.6, 95 per cent CI 1.3–5.2) and pneumothorax (RR 3.7, 95 per cent CI 1.8–7.7). Our data highlight the importance of the immediate postnatal period in infants with RDS and suggest that close attention to early stabilization of VLBW infants with RDS, may further reduce the mortality associated with this disorder.


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?


This article has been cited by other articles:


Home page
 PediatricsHome page
T. Wuhib, B. J. McCarthy, T. L. Chorba, T. A. Sinitsina, I. V. Ivasiv, and S. J.N. McNabb
Underestimation of Infant Mortality Rates in One Republic of the Former Soviet Union
Pediatrics, May 1, 2003; 111(5): e596 - 600.
[Abstract] [Full Text] [PDF]


Disclaimer:
Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.