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Journal of Tropical Pediatrics 1997 43(2):89-92; doi:10.1093/tropej/43.2.89
© 1997 by Oxford University Press
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Fetal Growth in Maternal Anaemia

P. N. Singla*, M. Tyagi*, Ashok Kumar*, D. Dash** and R. Shankar**

*Department of Paediatrics, Institute of Medical Sciences, Banaras Hindu University Varanasi-221 005, India
**Departments of Biochemistry, Institute ofMedical Sciences, Banaras Hindu University Varanasi-221 005, India

The effect of maternal iron deficiency anemia on fetal growth was studied in 54 anaemic (haemoglobin <11.0 g/dl) mothers. Twenty-two mothers served as controls (haemoglobin≥11.0 g/dl). All the women had singleton live births at term gestation. The maternal iron status was assessed by serum ferritin estimation. The birth weight, head circumference, chest circumference, mid-arm circumference, and crown heel length were significantly low in infants born to women with moderate (haemoglobin 6.1 ±8.5g/dl) and severe anaemia (haemoglobin ≤ 6.0 g/dl), in comparison to infants born to non-anaemic women. Similarly, birth weight, mid-arm circumference, and crown-heel length were significantly low in infants of women with depleted iron stores (serum ferritin <10 µg/l) than in infants of women with serum ferritin levels of 20 µg/l or more. All indices of fetal growth showed linear relationships with maternal haemoglobin, as well as with serum ferritin. The growth retarding effect of maternal anaemia was more on fetal birth weight and mid-arm circumference than on other anthropometric indices of the newborn.


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