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Journal of Tropical Pediatrics 1996 42(3):144-145; doi:10.1093/tropej/42.3.144
© 1996 by Oxford University Press
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Response of Egyptian Infants with Protein Calorie Malnutrition to Hepatitis B Vaccination

Yehia El-Gamal*,, Ragaa H. Aly**, Elham Hossny*, Eid Afify* and Dorreya El-Taliawy**

*Pediatric Department of Ain Shams University Cairo, Egypt
**Egyptian Organization for Biological Products & Vaccines Cairo, Egypt

Correspondence: Professor Yehia El-Gamal, 98 Mohamed Farid Street, Cairo 11111, Egypt

The response to recombinant hepatitis B vaccine was assessed in 31 seronegative infants (2–26 months old) with protein calorie malnutrition (PCM), compared with 13 seronegative age- and sex-matched healthy infants. Both groups received three 10 µg vaccine doses at 0, 1, and 6 months. At month 8, all healthy infants and 87 per cent (27 out of 31) of PCM infants were seroprotected. Thus, hepatitis B vaccination (Engerix-B, SmithKline Beecham Biologicals) can be used effectively in PCM for mass vaccination in developing communities.


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