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Journal of Tropical Pediatrics 1994 40(4):231-234; doi:10.1093/tropej/40.4.231
© 1994 by Oxford University Press
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Localized Extracranial Infections in Children with Acute Bacterial Meningitis

G. O. Akpede, MD, FWACP, FMC Paed (Nig)

Department of Paediatrics, College of Medical Sciences, University of Maiduguri PMB 1069, Maiduguri, Borno State, Nigeria

Twenty-four of 66 (363.6±116/1000) post-neonatal children with acute bacterial meningitis treated between August 1991 and November 1992 at the Emergency Paediatric Unit, University of Maiduguri Teaching Hospital, Nigeria, had co-existing localized extracranial infections (LEI). Nineteen had bronchopneumonia (of which 14 were in combination with other infections), two had dysentry and one each acute otitis media, orbital cellulitis, and purulent conjunctivitis. LEI were significantly more frequent in children ≤ 2 years, and in children with delayed presentation and delayed diagnosis after presentation. Mortality rate was higher in children with LEI (500 ± 200/1000) than in those without (102.6 ± 95.2/1000) (P< 0.001). There was no significant relationship between the incidence of LEI and the causative organisms of meningitis or nutritional status of children with meningitis. We conclude that co-existing LEI are not infrequent in children with acute bacterial meningitis; they contribute to delayed diagnosis and are associated with a poorer outcome.


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