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Journal of Tropical Pediatrics 1994 40(3):162-165; doi:10.1093/tropej/40.3.162
© 1994 by Oxford University Press
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Seasonal and Geographical Variations in the Growth Rate of Infants in China Receiving Increasing Dosages of Vitamin D Supplements

E. S. Feliciano, BSc*,, M. L. Ho, MS**, B. L. Specker, PhD**, G. Falciglia, PhD*, Qing-mei Shui***, Tai-an Yin*** and Xue-cun Chen, MD***

*Department of Health and Nutrition Sciences, College of Education, University of Cincinnati Cincinnati, Ohio, USA
**Department of Pediatrics, University of Cincinnati Medical Center Cincinnati, Ohio, USA
***Department of Maternal and Child Nutrition, Institute of Nutrition and Food Hygiene, Chinese Academy of Preventive Medicine Beijing, China

Correspondence:Ms Estrella S. Feliciano, Department of Anatomy and Cell Biology, University of Cincinnati, College of Medicine, Cincinnati, Oh 45267–0541, USA.

In theory, sunshine exposure is sufficient to maintain normal vitamin D concentrations for the optimal growth of newborn infants. To determine whether season of birth, latitude (north v. south) and increasing dosages of vitamin D supplements would influence the growth rate for the first 6 months of life, 255 healthy fall-and spring-born infants from two northern and two southern cities in China were randomly assigned to receive either 100, 200, or 400 IU of vitamin D a day. The study showed that season of birth and dose of vitamin D did not affect the growth rate of infants born in the same latitude, but a significant difference was found in the gain in length over the 6-month period between infants from the north and infants from the south (P=0.0001). Regional differences among the Chinese people, other than sunshine exposure, may have influenced the difference in length gain


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