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Journal of Tropical Pediatrics 1990 36(6):294-298; doi:10.1093/tropej/36.6.294
© 1990 by Oxford University Press
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Malnutrition and Childhood Tuberculosis

M. Vijayakumar, MBBSDCh MSc (Appl Nutr), P. Bhaskaram, MD (Ped)* and P. Hemalatha, MBBS

National Institute of Nutrition, Indian Council of Medical Research Jamai Osmania, P.O. Hyderabad 500007, India

Dr P. Bhaskaram

Cell-mediated immune status (CMI) of sixty-five children suffering from various clinical forms of tuberculosis and thirty age-and sex-matched healthy children aged between 1 and 5 years was investigated to understand the role of malnutrition in tuberculosis. A significant association between severe malnutrition and severe forms of infection was observed. Data on CMI showed immunosuppressive effect of tuberculosis per se in all children. Well nourished children had similar CMI status irrespective of the severity of the disease while malnourished children with severe forms of disease showed lowest CMI response. These data suggest not only the synergistic interactions of malnutrition and tuberculosis, but the contributory role of malnutrition in causing more sever immuno suppression. The results point out the importance of better nutritional status of the child in preventing the severe forms of the disease.


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