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Journal of Tropical Pediatrics 1990 36(6):283-286; doi:10.1093/tropej/36.6.283
© 1990 by Oxford University Press
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Pediatric HIV-1 Disease in a Kampala Hospital

O. Müller*,, P. Musoke**, G. Sen*** and Rita Moser**

*League of Red Cross and Red Crescent Societies in Geneva Sitwezerland
**Rubaga Hospital in Kampala Uganda
***Free University of Berlin FRG

*German Red Cross Society, 1000 Berlin 61, Baerwaldstraße 55, West Germany

Data of pediatric patients screened for HIV-1 infection between 1985 and 1989 were studied retrospectively in one of the major mission hospitals of Kampala (Uganda). Symptomatic HIV-1 infection was mainly acquired perinatally and was diagnosed in 87 per cent in children under 2 years of age. The mortality rate was 40 per cent in pediatric in-patients with symptomatic HIV-1 infection as compared to 12 per cent in overall pediatric inpatients. Symptoms included in the WHO clinical case definition for pediatric AIDS were mainly insensitive, unspecific and demonstrated a low positive predictive value. There was no difference in the prevalence of malaria and measles between HIV-1 positive and HIV-1 negative children.


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S. B Lucas, C. S Peacock, A. Hounnou, K. Brattegaard, K. Koffi, M. Honde, J. Andoh, J. Bell, and K. M De Cock
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