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Journal of Tropical Pediatrics 1990 36(5):251-255; doi:10.1093/tropej/36.5.251
© 1990 by Oxford University Press
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Investigation of Serum Vitamin A Levels of Children who had a History of Recurrent Diarrhoea and Acute Respiratory Infections in Ankara

B. Büyükgebiz, MD, PhD, I. Özalp, MD and O. Oran, MD

Hacettepe University Children's Hospital Ankara, Turkey

Vitamin A deficiency iS considered a widespread public health problem among preschool children In the developing countries. A limited number of studies reveal an association between xerophthalmia and significant systemic diseases including protein-energy malnutrition, diarrhoea, and acute respiratory infections. The present study was carried out to assess the vitamin A status of preschool children who have a history of recurrent acute respiratory infections and diarrhoea. We have already shown that serum vitamin A levels of all the study groups were lower than the control group (P<0.001) and the detailed statistical analyses made clear that malnutrition is the major contributing factor (P<0.0Ol) although Infections also have a negative effect on senim vitamin A levels (P<0.01). We have also shown that subclinical vitamin A deficiency is a problem of public health importance in this region, since about 64 per cent of the children examined were found to have low levels of serum vitamin A (<20 µg/dl).


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