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Journal of Tropical Pediatrics 1988 34(5):248-250; doi:10.1093/tropej/34.5.248
© 1988 by Oxford University Press
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Serum Lysozyme and Phosphatases in Children with Schistosoma haematobium Infections

Olakunle O. Kassim, PhD, MPH

Department of Microbiology, Howard University College of Medicine Washington DC 20059, USA

Sera from 94 primary school children with urinary schistosomiasis and a control group of 58 children were analysed for activities of lysozyme, alkaline phosphatase, total acid, and tartrate-resistant acid phosphatases. Lysozyme levels for the two groups ranged from 150 to 770µg/ml, and the mean values were not significantly different. However, Schistosoma haematobium-infected children had a mean alkaline phosphatase activity of 59.3 IU/I, a mean level of 5.13 IU/I for total acid phosphatase and a mean value of 2.25 IU/I for tartrate-resistant acid phosphatase. These values represent significant increases over those obtained for the control group and serve as indices of the hepatic and bladder inflammatory processes associated with urinary schistosomiasis.


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