© 1987 by Oxford University Press
research-article |
Necrotizing Enterocolitis after the Neonatal Period
Department of Pathology, Red Cross War Memorial Children's Hospital Cape Town, South Africa
Correspondence to: R. O. C. Kaschula, Department of Pathology, Red Cross Children's Hospital, Rondebosch, Cape Town, 7700 South Africa.
Necrotizing enterocolitis (NEC) is well described in neonates, but there have been few reports in children after the neonatal period.
A retropsective autopsy analysis of 29 cases of NEC seen over the period 1957 to 1982 was undertaken and histological findings were correlated with clinical data.
Twenty-two were less than one year of age. Malnutrition (weight <80 per cent expected weight for age) was present in 22 of 27 cases. Dehydrating diarrhoea and hypovolaemic shock were common preceding illnesses. Abdominal distension, peritonism, and frank blood in the stools were less common.
Histological evaluation of lymph node and spleen showed lymphocyte depletion in most patients and this was particularly common in malnourished children.
Preceding diarrhoeal diseases, underlying malnutrition, and reduced lymphoid cellularity are frequently present in the older child with NEC.