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Journal of Tropical Pediatrics 1985 31(1):54-58; doi:10.1093/tropej/31.1.54
© 1985 by Oxford University Press
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A Review of Thyroid Disorders in Singapore Children

Siok Hoon Tan, MBChB (Manc), MMed(Paed), Senior Lecturer and Senior Professor and Head and Hock Boon Wong, MBBS, FRCP, FRACP, DCH, PJG, PPA, Senior Lecturer and Senior Professor and Head

Department of Paediatrics, National University of Singapore

Thyroid disorders constitute a large proportion of endocrine problems in children. In the Endocrine Clinic of the University Department of Paediatrics, 102 children with thyroid disorders were seen from 1976 to 1982. Forty-two point two per cent had hypothyroidism, 35.3 per cent had hyperthyroidism and 17.6 per cent had non-toxic goitres. There was a female preponderance. Indians showed a higher prevalence of hypothyroidism and non-toxic goitre while hyperthyroidism was commoner in the Chinese.

Early diagnosis and treatment of congenital hypothyroidism is important to prevent mental retardation. The majority of our patients with congenital hypothyroidism were diagnosed only after infancy. Half of these patients showed some degree of mental retardation. Hence the importance of a newborn screening programme for hypothyroidism is emphasized.

Only 28 per cent of the hyperthyroid patients did not relapse after an adequate course of medical treatment. Surgery was performed in only one patient who had failed medical treatment, and had a large goitre.


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