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Journal of Tropical Pediatrics 1982 28(5):235-239; doi:10.1093/tropej/28.5.235
© 1982 by Oxford University Press
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Chemistry of a Nigerian Herbal Preparation (Cow's Urine Concoction) I

F. O. AYORINDE, Faculty of Pharmacy, J. W. AVERY, A. D. ADEKILE, J. A. OJEWOLE and O. O. ODEBIYI, Faculty of Pharmacy

Department of Chemistry Howard University Washington D.C. 20059
Department of Pediatrics and Child Health Ife University Teaching Hospitals Complex Ile-Ife, Nigeria
University of Ife Ile-Ife, Nigeria

Cow's urine concoction is a traditional herbal preparation commonly administered to convulsing children by the Yoruba-speaking people of Nigeria. Its use is, however, usually complicated by severe poisoning.

Methylene chloride extracts from two samples of the preparation were analyzed by direct application of gas chromatography-mass spectrometry (gc-ms). Gas chromatographic traces indicated over fifty compounds, the major constituents include nicotine, p-cresol and benzoic acid. The toxicity of these compounds is correlated with the clinical features of cow's urine concoction poisoning.


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Composition of Cow's urine
Amritpal Singh Saroya, et al.
Journal of Tropical Pediatrics, 22 Apr 2006 [Full text]

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