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Journal of Tropical Pediatrics 1982 28(1):8-10; doi:10.1093/tropej/28.1.8
© 1982 by Oxford University Press
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A Comparison of the Effects of Glucose and Sucrose on Cholera Toxin Induced Secretion in the Rat Jejunum in vivo

J. KSIAZYK, P. J. MILLA and J. T. HARRIES

Institute of Child Health and the Hospital for Sick Children Great Ormond Street, London, W.C.1

The effects of glucose and sucrose on cholera toxin (CT) induced fluid secretion in the rat jejunum in vivo were compared. Both glucose and sucrose reversed net secretion to absorption, and were equally effective. CT had no effect on sugar absorption, or on sucrose hydrolysis. These data, together with other considerations, provide a rational basis for the inclusion of sucrose rather than glucose in oral rehydration solutions.


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