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Journal of Tropical Pediatrics 1974 20(3):126-129; doi:10.1093/tropej/20.3.126
© 1974 by Oxford University Press
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Effectiveness of Measles Vaccine given simultaneously with DTP

RICHARD MARSHALL, A.B., JEAN-PIERRE HABICHT, M.D., M.PH., PH.D., PHILIP J. LANDRIGAN, M.D., WILLIAM H. FOEGE, M.D. and HERMAN DELGADO, M.D.

School of Medicine, University of California San Diego, La Jolla, California 92037
División de Desarrollo Humano, Institute de Nutrición de Centro América y Panamá, Guatemala Guatemala, C.A.
Field Services Branch, Epidemiology Programme, Centre for Disease Control, U.S. DHEW Atlanta, Georgia 30333
Director, Smallpox Eradication Programme, Centre for Disease Control Atlanta, Georgia 30333

Rural Guatemalan children (101) 1 to 6 years of age were given either measles vaccine alone, measles vaccine with DTP, or DTP alone. Measles seroconversion rates and geometric mean HI antibody titres did not differ significantly between children who received measles vaccine alone (86 per cent) and those who received measles vaccine with DTP (85 per cent). Nutritional status also had no effect on seroconversion. These findings indicate that further attenuated live measles virus vaccine may be given with DTP in mass immunization campaigns without reducing the effectiveness of measles immunization.


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